Alert date July 29, 2021

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Nearly 3% of medical workers in a new Israeli study contracted COVID-19 even though they were vaccinated, and 19% of them still had symptoms six weeks later.

The study followed about 1,500 Israeli health care workers for four months after they received the Pfizer-BioNTech vaccine.

Anyone who tested positive more than 11 days after the second dose was considered a breakthrough case.

Dr. Eric Topol, a cardiologist who founded and directs the Scripps Research Translational Institute in California. said current vaccines are great at preventing serious infection deep in the lungs, but not at blocking infection in the upper airways.

What’s needed, he said, is a nasal-spray vaccine that would stop the coronavirus from taking hold at all.

“Those who are vaccinated did everything right, but some are going to go on to long-COVID, and that’s really unfortunate.”

Topol said the best protection is to get vaccinated and practice social measures like wearing a mask.

Dr. Ashish Jha, dean of the Brown University School of Public Health, said he is troubled by the fact that young, healthy people would get so-called breakthrough infections within a few months of vaccination.

Scientists expected protection to wane over time, and they expected the vaccines to be less effective among older people and those with pre-existing health conditions. But that’s not who got sick in this study.

Dr. Ashish Jha, said he finds it concerning – though not conclusive – that people had lingering symptoms weeks after getting sick.

“There really may be a risk here, but we don’t know how big a risk and how much of a problem it is,” he said.

Although the vaccines were never expected to be perfect, the findings raise questions about their protection and suggest that even vaccinated people could experience long-term symptoms such as such as fatigue, brain fog and shortness of breath.

Most of the people in the study who got sick had mild symptoms, and none were hospitalized.

The good news is none of the 39 people who got infected passed the coronavirus on to anyone else, according to the study, published Wednesday in the New England Journal of Medicine.